SynaptiX: Systemsbiology of Forgetting

 

Acquiring new memories is essential for adaption to novel and changing environments. However it is as important to be able to forget and erase memories that are unused or no longer important. So far, forgetting has been considered as an inevitable property of the neuronal substrate and the underlying network. But recent data from the fruit fly suggests that the forgetting rate is actively tuned by protein syntheses within a single neuron. When the environment changes quickly, the passive forgetting of memories is more rapid. The project investigates the biological bases of this forgetting both from an experimental and theoretical point of view